Riggs R, O'Dell M, Turner J, Crawford A, Abrams C; International Conference on AIDS.
Int Conf AIDS. 1990 Jun 20-23; 6: 459 (abstract no. 4023).
The Graduate Hospital, Philadelphia, PA, USA
OBJECTIVE: This study examined the interrater reliability of the Karnofsky Performance Status (KPS) in the HIV population. METHODS: Persons with documented CDC Groups II-IV HIV disease were identified in a medical setting. Each was evaluated by either 2 physicians (P-P) or a physician and physician's assistant (P-PA). KPS scores were independently determined and demographic data obtained. The sample consisted of 77 men: primarily homosexual/bisexual and white. The average age was 35.6 years and each CDC HIV Group made up approximately one-third of the sample. Statistical analysis was performed using the Spearman rank order correlation coefficient (SROCC) and by observing trends between raters. RESULTS: The average KPS score for the sample was 88.6. The overall SROCC was 0.90. Perfect agreement was seen in 52.4% of paired scores with 44.3% and 2.4% differing by 1 and 2 levels, respectively. The reliability of the KPS was not significantly affected by the age, degree or disability, or CDC Group of the person assessed. Trends were observed in the direction of disagreement between P-P and P-PA, with the former tending to be higher. CONCLUSION: We conclude the KPS has adequate interrater reliability in the HIV population. It should then be a reliable indicator of gross function for clinical drug trials, general outcome research, and as a gross measure of quality of life. Reliability testing in larger, more diverse sample would be beneficial. Further research needs to be conducted examining the validity of the KPS in the HIV population.
Publication Types:
Keywords:
- Acquired Immunodeficiency Syndrome
- Disabled Persons
- HIV Infections
- HIV Seropositivity
- Humans
- Karnofsky Performance Status
- Male
- Population Groups
Other ID:
UI: 102197410
From Meeting Abstracts