Pillonel J, Courouce AM, Lemaire JM, Brunet JB; International Conference on AIDS.
Int Conf AIDS. 1994 Aug 7-12; 10: 135 (abstract no. PA0158).
National Network of Public Health, France.
OBJECTIVES: 1) to determine the prevalence of HTLV-I/II antibodies among French blood donors (BDs) since the beginning of the systematic screening (15th July 1991) in Continental France (CF). 2) to study the epidemiological characteristics of HTLV-I/II seropositive BDs. METHOD: Since July 1991, the monitoring of HTLV-I/II mandatory screening activity was organized in France. For each BD confirmed as HTLV-I/II positive (Elisa + WB), the BT centers provided routinely informations on age, sex and results of other mandatory tests (anti-HIV, HBsAg, anti-HBc, anti-HCV) while informations on geographical origin and risk factor were recorded through post-test interview. RESULTS: The prevalence of HTLV-I/II per 10,000 blood donations was: TABULAR DATA. SEE ABSTRACT VOLUME. From 1991 to 1993, all the 165 HTLV positive BDs identified in overseas territories were HTLV-I. In CF, 5 were HTLV-II (1 born in Cameroon + 4 intravenous drug addicts) and 170 were HTLV-I. Among the 170 HTLV-I found in CF, 50% were originating from CF, 38% from the Caribbean, 5% from Africa, 2% from South-America and 5% from other or unknown countries. Among the 85 BDs originating from CF, 79% had a sexual partner from Caribbean. Due to previously targeted screening policy and other mandatory tests, 49% of the infected units in CF would have been discarded in the absence of universal screening. CONCLUSION: HTLV prevalence is low in CF where the infection is mainly due to HTLV-I (97%) and linked to endemic areas, mainly the Caribbean. As the prevalence decreased between 1991 and 1993, the cost per avoided contamination with the new screening policy went up from 1.34 to 4.24 million F. francs.
Publication Types:
Keywords:
- Africa
- Blood Donors
- Cameroon
- Caribbean Region
- Communicable Diseases
- Deltaretrovirus
- Deltaretrovirus Antibodies
- Deltaretrovirus Infections
- Enzyme-Linked Immunosorbent Assay
- France
- HIV
- HIV Infections
- HIV Seropositivity
- HTLV-I Infections
- Hepatitis B Antibodies
- Human T-lymphotropic virus 1
- Human T-lymphotropic virus 2
- Prevalence
- Risk Factors
- South America
Other ID:
UI: 102208222
From Meeting Abstracts