Brites C, Pedroso C, Amaral V, Pedral-Sampaio DB, Harrington WJ, Bina JC, Silva N, Badaro R; Conference on Retroviruses and Opportunistic Infections.
Program Abstr 4th Conf Retrovir Oppor Infect Conf Retrovir Oppor Infect 4th 1997 Wash DC. 1997 Jan 22-26; 4th: 99 (abstract no. 186a).
Federal University of Bahia-Salvador, Bahia, Brazil.
Objective: To evaluate the frequency of HTLV-I co-infection among AIDS patients presenting severe scabies. Patients and methods: We tested all AIDS patients admitted to the Infectious Diseases Unit (IDU) of University with a diagnosis of severe scabies, for HTLV-I antibodies, using an EIA kit (Coulter Corp, FL). The positive samples were confirmed by Western blot (Cellular Products, NY). We compared the prevalence of HTLV-I antibodies in this group with the frequency of HTLV-I infection in a large cohoort of HIV-1 infected subjects. Results: The IDU cares an average of 250 AIDS in patients/year. From May 1994 through November, 1995, the IDU admitted to AIDS patients (7 men) presenting severe, disseminated scabies. The 10 patients were positive for HTLV-I , while the prevalence of HTLV-I co-infection among 895 individuals previously tested was only 11.4% (p is less than 0.000001, Yates corrected). All patients with severe scabies had a history of intravenous drug use (IVDU). There was an association between IVDU and scabies (among the 895 subjects 19.2% were IVDU, and 33.7% of them had HTLV-I co-infection, against 100% of scabies patients (p=0.00005). Conclusions: Severe scabies among AIDS patients was a strong predictor for HTLV-I co-infection, in Bahia, Brazil. Also, we detected a significantly higher frequency of IVDU in this group, compared with a larger sample of HIV-HTLV-I co-infected patients.
Publication Types:
Keywords:
- Acquired Immunodeficiency Syndrome
- Blotting, Western
- Brazil
- HIV
- HIV Antibodies
- HIV Infections
- HIV Seropositivity
- HIV Seroprevalence
- HIV-1
- HTLV-I Antibodies
- HTLV-I Infections
- Human T-lymphotropic virus 1
- Humans
- Immunoenzyme Techniques
- Male
- Prevalence
- Scabies
- Substance Abuse, Intravenous
Other ID:
UI: 102225364
From Meeting Abstracts