Perez F, Orne-Gliemann J, Mukotekwa T, Miller A, Glenshaw M, Dabis F; International Conference on AIDS.
Int Conf AIDS. 2002 Jul 7-12; 14: abstract no. TuPeF5416.
ISPED - Universite Bordeaux 2, Bordeaux, France
ISSUES: In Zimbabwe, it is estimated that each year 50 000 new-borns acquire HIV infection through perinatal transmission. Simplified antiretroviral regimens for reducing mother-to-child transmission (MTCT) of HIV-1 have been proposed for resource poor countries. There is still limited data on prevention of MTCT (PMTCT) in rural settings. DESCRIPTION: Since August 2001, Murambinda Hospital (120 beds) is providing to the northern Buhera district population (n=200 000): integrated voluntary HIV counselling and testing services (VCT) to all attending pregnant women and their partners, single dose of nevirapine (NVP) to HIV infected mother and infants (HIV-NET 012 protocol), infant feeding counselling and cotrimoxazole (CMX) prophylaxis to HIV infected mothers and infants. These services are being promoted at a district level through community support groups. LESSONS LEARNED: From August 15, 2001 to January 15, 2002, 1 651 pregnant women were offered VCT in the hospital, 497 women were pre-test counselled (30%) among which 94% tested for HIV. The overall HIV prevalence was 22%. Of all 104 HIV-infected women, 28 have delivered during this period; 100% opted to breastfeed their baby. NVP therapy was accepted by 75% of eligible mother-infant pairs. Main reasons for women to refuse pre-test counselling were: a previous HIV test (41%) and the need to consult their husband (21%). Seven women who gave birth did not take NVP (25%): three did not identify themselves as HIV infected at labour and one delivered elsewhere. RECOMMENDATIONS: Integration of PMTCT activities is well accepted within Murambinda Mission Hospital. Qualitative studies are planned to increase adherence to VCT and reduce missed opportunities at each phase of the intervention. Specific attention is being given to the potential of up-scaling activities at the district level so as to improve coverage and follow-up.
Publication Types:
Keywords:
- AIDS Vaccines
- Acquired Immunodeficiency Syndrome
- Antiretroviral Therapy, Highly Active
- Child
- Counseling
- Disease Transmission, Vertical
- Female
- Foundations
- HIV Infections
- HIV Seropositivity
- HIV-1
- Hospitals
- Humans
- Infant
- Mothers
- Nevirapine
- Pregnancy
- Prevalence
- Rural Population
- Zimbabwe
- drug therapy
- economics
- therapy
- transmission
Other ID:
UI: 102256600
From Meeting Abstracts