Anderson VM, Lee H, Greco MA, Arroyo A; International Conference on AIDS.
Int Conf AIDS. 1989 Jun 4-9; 5: 494 (abstract no. B.583).
SUNY Health Science Center, Interfaith Medical Center, Brooklyn, NY, USA
OBJECT: To report the clinicopathologic correlations of ranula cysts in children with AIDS. METHOD: Two cases are reported: 1) Patient 1 had lymphadenopathy and lymphocytic interstitial pneumonitis (LIP) at age 1 year and a 3cm in diameter, sublingual, ranula cyst which was excised at age 2. Within 3 weeks it reoccurred only to spontaneously disappear two months later. 2) Patient 2 had LIP with corpulmonale and hypoxia at age 2 years. Following treatment with steroids, a 1cm in diameter ranula cyst disappeared. RESULTS: The sublingual excisional biopsy of the collapsed cyst revealed a fibrous shell containing lymphocytes and plasma cells that also infiltrate islands of mixed salivary gland tissue containing ectatic ducts lined by pseudostratified epithelium. CONCLUSION: Ranula cyst resembles cystic parotid lymphoepithelial lesions described in adults with AIDS. Ductal obstruction by inflammatory cells is part of the spectrum of steroid-sensitive, extranodal, polyclonal, polymorphic, B cell lymphoproliferation most often presenting as EBV related LIP in children with AIDS.
Publication Types:
Keywords:
- Acquired Immunodeficiency Syndrome
- Adult
- B-Lymphocytes
- Child
- Cysts
- Humans
- Lip
- Lymphoproliferative Disorders
- Parotid Gland
- Ranula
- organization & administration
Other ID:
UI: 102178465
From Meeting Abstracts