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Strucure of fatal outcomes and patological anatomy in HIV-infected patients in Moscow.

Tishkevich OA, Shakhgildian VI, Parkhomenko YG; International Conference on AIDS (15th : 2004 : Bangkok, Thailand).

Int Conf AIDS. 2004 Jul 11-16; 15: abstract no. B11212.

Clinical Infection Hospital, Moscow, Russian Federation

Background: The important problem for clinicians is to determine the frequency of secondary and opportunistic diseases which lead to the fatal outcome in patients with HIV-infection. It is also critical to determine pathomorphological changes in organs. Methods: The results of 537 autopsies performed in 2nd Moscow Infection Hospital since 1991 to 2003 were analyzed 41.3% of patients died in 2002 - 2003. The most common reason of death in the HIV-infected patients was tuberculosis (34.5%). CMV-infection was most often opportunistic disease in HIV-infected patients (15.8%). Also toxoplasmosis (8.2%), PCP (1.1%), cryptococcus infection (1.1%), HSV-encephalitis (0.4%), PML (0.4%), Kaposi sarcoma (6.9%), malignant neoplasms, among which prevailed lymphomas (6.9%) were diagnosed. In 2002 and 2003 the significant decrease in number of fatal outcomes because of sepsis in intravenous drug users with early stages of HIV-infection (2000 -13.9%, 2003 - 0.8% cases). During last two years the number of liver cirrhosis, hepatic decompensation and liver-related death in patients with HIV/HCV co-infection was increased (2000 -0%, 2001 - 2.6%, 2002 - 7.1%, 2003 - 9.9% cases). Conclusions: During last years the most common reasons of death in patients with HIV-infection in Moscow were tuberculosis, CMV-infection, toxoplasmosis, Kaposi sarcoma. The amount of malignant lymphomas has increased. Since 2002 the number of the patients with sepsis significantly decrease, but the frequency of liver-related death in HIV/HCV co-infected patients has increased.

Publication Types:
  • Meeting Abstracts
Keywords:
  • Acquired Immunodeficiency Syndrome
  • Cytomegalovirus Infections
  • Fatal Outcome
  • HIV
  • HIV Infections
  • HIV Seropositivity
  • Humans
  • Moscow
  • Sarcoma, Kaposi
  • Substance Abuse, Intravenous
  • Toxoplasmosis
  • Tuberculosis
Other ID:
  • GWAIDS0032418
UI: 102276632

From Meeting Abstracts




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