Nair P, Johnson J, Hines S, Alger L, Seiden S; International Conference on AIDS.
Int Conf AIDS. 1989 Jun 4-9; 5: 127 (abstract no. W.A.P.47).
Department of Pediatrics, University of Maryland School of Medicine, Baltimore, Maryland, USA
OBJECTIVE: To correlate maternal and neonatal characteristics with perinatal transmission of HIV. METHODS: In a prospective study of perinatal transmission infants born to seropositive women were assayed for anti-HIV IgG, IgM, and HIV antigen at 2, 4, 6, 9 and 12 months of age. Data on 35 infants born to HIV positive women, 15 of whom show evidence of being infected, are presented. RESULTS: All mothers of infected infants and 90% of mothers of non-infected infants had history of I/V drug use. There was no significant difference in age, education, type of family, marital status, parity or age at first pregnancy. The incidence of STD infections during pregnancy was higher in mothers of infected babies (40% vs 25%) and their participation in methadone treatment programs was significantly lower (37% vs 55%). Birth weights, gestational ages and perinatal problems were similar in both groups except for neonatal abstinence syndrome due mostly to methadone withdrawal which was higher in the non-infected group (55% vs 27%). CONCLUSION: In this group of infants transmission of HIV appears to be associated with maternal lifestyle characteristics.
Publication Types:
Keywords:
- Acquired Immunodeficiency Syndrome
- Birth Weight
- Female
- HIV Infections
- HIV Seropositivity
- Humans
- Infant
- Infant Mortality
- Infant, Newborn
- Mothers
- Pregnancy
- Prospective Studies
Other ID:
UI: 102176334
From Meeting Abstracts