Marques LP, Santos OR, Lopes GS, Oliveira AV, Fialho F, Madeira EP; International Conference on AIDS.

Int Conf AIDS. 1989 Jun 4-9; 5: 268 (abstract no. M.B.P.281).

Clinica Medica III, Escola de Medicina e Cirurgia, UNI-RIO, Brasil

AIDS-associated nephropathy is characterized by the presence of focal end segmental glomerulosclerosis (FSGS) with rapid progression to terminal renal failure. We study 303 HIV-infected patients, 280 men and 23 women. Risk factors were: 221 homosexuals, 37 hemophiliacs, 14 unknown, 13 heterosexual contacts, 12 blood transfusion, 6 IV drug addicts. We found nephrotic syndrome (NS) in 3 (0.9%) associated with azotemia in 2 (moderate in 1 and severe in 1). Renal biopsy showed FSGS in 2 and diffuse glomerulosclerosis in 1. All progressed to terminal renal failure, 2 died, 14 months after the onset of NS. One has been submitted to maintenance hemodialysis for ten months. In 2 patients (IV drug addict and unknown risk factor) the diagnosis of HIV infection was only possible when they presented opportunistic infections, 3 and 4 months after the onset of NS. We conclude that NS may be the initial manifestation of HIV disease and we suggest that anti-HIV tests should be done in all adult nephrotic patients.

Publication Types:

• Meeting Abstracts

Keywords:

• AIDS-Associated Nephropathy
• Acquired Immunodeficiency Syndrome
• Adult
• Blood Transfusion
• Female
• Glomerulonephritis
• HIV Infections
• HIV Seropositivity
• Humans
• Kidney Diseases
• Kidney Failure, Acute
• Male
• Nephrotic Syndrome
• Renal Dialysis
• Risk Factors
• Uremia

Other ID:

• 00124489

UI: 102177135

From Meeting Abstracts