Lacroix M, Dwyer RJ, Fauvel M; International Conference on AIDS.
Int Conf AIDS. 1989 Jun 4-9; 5: 477 (abstract no. Th.B.P.371).
IAF BioChem International Inc., Montreal, Canada, H7V 1B7
OBJECTIVE: Compare the ability of a new peptide-based ELISA with RIPA for the detection of early antibodies to HIV-1. METHODS: Serum samples are from two seroconversion panels. Each specimen was carefully characterized for the presence or absence of antibodies to HIV by the FDA licensed ELISA test kits then available as well as by IFA and WB. IAF BioChem's combined HIV-1/HIV-2 antibody detection kit is a peptide-based ELISA whose characteristics and performance are described elsewhere at this meeting. RIPA procedures are as described (Ozanne and Fauvel, J. Clin. Microbiol. 26: 1496, 1988). RESULTS: TABULAR DATA, SEE ABSTRACT VOLUME. CONCLUSION: IAF BioChem's ELISA is more sensitive than WB and viral lysate ELISA and is comparable to RIPA in the early detection of antibodies to viral glycoproteins.
Publication Types:
Keywords:
- Acquired Immunodeficiency Syndrome
- Enzyme-Linked Immunosorbent Assay
- HIV
- HIV Antibodies
- HIV Antigens
- HIV Core Protein p24
- HIV Envelope Protein gp120
- HIV Envelope Protein gp41
- HIV Infections
- HIV Seropositivity
- HIV-1
- HIV-2
- Immunologic Techniques
- Indicators and Reagents
- Radioimmunoprecipitation Assay
- Reagent Kits, Diagnostic
- immunology
Other ID:
UI: 102178379
From Meeting Abstracts