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HIV wasting syndrome in the United States.

Nahlen B, Nwanyanwu O, Chu S, Berkelman R; International Conference on AIDS.

Int Conf AIDS. 1991 Jun 16-21; 7: 34 (abstract no. M.C.47).

Centers for Disease Control (CDC), Atlanta, Georgia, USA

OBJECTIVE: To describe the characteristics of AIDS patients reported with HIV wasting syndrome (WS) in the United States. METHODS: Adult/adolescent AIDS patients (greater than 13 years) reported with WS to CDC from 9/87 through 12/90 were compared to those without WS (non-WS). RESULTS: Of the 85,846 AIDS patients reported since 9/87, a total of 5.5% had WS as the only AIDS-indicator condition (AI), and 10.5% had WS plus at least one other AI. Overall, there were no differences noted by race, but WS patients were significantly more likely to be female and to be in the 13-19 and 60-69 year age groups. WS patients were also more likely to be intravenous drug users (IVDUs) or sex partners of IVDUs, and were more likely than non-WS patients to have died. The proportion of AIDS patients reported with WS by geographic distribution ranged from a low of 13.3% in the mid-Atlantic states to a high of 50.1% in Puerto Rico. The AIs most strongly associated with WS were candidiasis of the lungs (OR 3.3; CI 3.0-3.6), esophageal candidiasis (OR 3.3; CI 3.1-3.4), HIV encephalopathy (OR 3.0; CI 2.8-3.2), and coccidioidomycosis (OR 2.5; CI 1.8-3.4); there was no association with mycobacterial disease. CONCLUSIONS: Overall, 16.0% of AIDS cases reported since 9/87 had WS as a diagnosis. The association of WS with IV drug use and the gender and geographic differences may be related to differences in diagnostic or reporting practices and/or access to medical care.

Publication Types:
  • Meeting Abstracts
Keywords:
  • AIDS Dementia Complex
  • Acquired Immunodeficiency Syndrome
  • Adolescent
  • Adult
  • Female
  • HIV Wasting Syndrome
  • Humans
  • Puerto Rico
  • Substance Abuse, Intravenous
  • Substance-Related Disorders
  • United States
  • Werner Syndrome
Other ID:
  • 1004791
UI: 102182059

From Meeting Abstracts




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