Rabello AL, Lambertucci JR, Katz N, Noce TR, Toledo AC, Greco DB; International Conference on AIDS.

Int Conf AIDS. 1991 Jun 16-21; 7: 259 (abstract no. M.B.2308).

Immunodeficiency Clinic, Infectious and Parasitic Diseases Service, Brazil

OBJECTIVE: To evaluate in a retrospective study the parasitological and serological positivity to S. mansoni in an endemic area and its relation to the various clinical phases of HIV infection in a high risk population. METHODS: From 1986 to 1989, 886 individuals who came spontaneously to the Immunodeficiency Clinic in Belo Horizonte, were examined. After proper consent, they were tested for HIV (ELISA and Western blot), the stools were examined (Hoffman Pons & Janer) and ELISA for antibodies do S. mansoni adults worms (ESM) was performed. RESULTS: The individuals were classified in relation to HIV:542 (63%) were negative; 144 (17%) asymptomatic; 47 (5%) PGL, 79 (9%) ARC and 54 (6%) AIDS. Viable Schistosoma eggs were identified in 48 out of 711 (6.8%) and ESM was positive in 475/866 (54.8%). The presence of S. mansoni eggs was significant higher (p less than 0.05) in the groups HIV negative/HIV positive asymptomatic when compared with PGL, ARC and AIDS combined. ESM was not different in the various groups and there was no difference in the clinical presentation of schistosomiasis. CONCLUSION: The smaller number of positive stool exams in PGL, ARC and AIDS may be secondary to the interference of cellular immunosuppression in the excretion of S. mansoni eggs, as reported in mice. A prospective study is being established to follow the patients with dual infections.

Publication Types:

• Meeting Abstracts

Keywords:

• AIDS-Related Complex
• Acquired Immunodeficiency Syndrome
• Adult
• Animals
• Brazil
• Enzyme-Linked Immunosorbent Assay
• HIV Infections
• HIV Seropositivity
• Humans
• Mice
• Prospective Studies
• Retrospective Studies
• Schistosomiasis
• Schistosomiasis mansoni

Other ID:

• 1230891

UI: 102183228

From Meeting Abstracts