Patey O, Salvanet A, Serrhini A, Breuil J; International Conference on AIDS.
Int Conf AIDS. 1992 Jul 19-24; 8: 98 (abstract no. PuB 7294).
Ch. Lafaix CHI, Villeneuve Saint Georges.
Ophthalmological disorders are frequent in AIDS patients, especially Cytomegalovirus (CMV) and Toxoplasma gondii (Tg) choroidopathies. PCP was the most frequent infection in HIV infected patients before primary prophylaxis. Many extrapulmonary PC infections had been described with Pentamidine aerosolized. CASE: A 43 year old man developed in May 1991 a tuberculosis adenitis and Kaposi sarcoma of scarpa. HIV serology was positive. He received antituberculosis therapy and Zidovudine. Fundoscopy was normal. In December 1991, he presented a PCP. Fundus examination showed bilateral yellow lesions. Lesions appeared on fluorescein angiogram with early hypofluorescence and with late staining. After therapy with high doses of cotrimoxazole pulmonary abnormalities disappeared and funduscopy remained unchanged. DISCUSSION: PCP occurred in 80% of AIDS patients before primary prophylaxis, but funduscopy was not systematic. With the development of pendamidine aerosolized prophylaxis some extrapulmonary location of PC infection, including choroiditis, were described. They were unusually associated with acute PCP. Choroiditis lesions are yellow with irregular borders bilateral and posterior to the equator. They were not associated with any vitreous inflammation. They became pale yellow during specific therapy and can disappeared after several months. CMV and Tg choroiditis are very different and tuberculosis lesions (Bouchut tubercule) can be eliminated in our patient because of the lack of disseminated tuberculosis which was treated for 4 months. CONCLUSION: Fundus examination should be done during all acute PCP ans PCP primary prophylaxis with Pentamidine aerosolized, for early diagnosis of PC choroiditis and disseminated infection.
Publication Types:
Keywords:
- AIDS-Related Opportunistic Infections
- Acquired Immunodeficiency Syndrome
- Choroid Diseases
- Choroiditis
- HIV Seropositivity
- Humans
- Infection
- Male
- Opportunistic Infections
- Pentamidine
- Pneumonia
- Pneumonia, Pneumocystis
- Sarcoma, Kaposi
- Toxoplasmosis, Cerebral
- Trimethoprim-Sulfamethoxazole Combination
- Tuberculosis
- Zidovudine
Other ID:
UI: 102202297
From Meeting Abstracts