Hooi AY, Lawlor F, Meadway JV, Wisdom AR; International Conference on AIDS.
Int Conf AIDS. 1994 Aug 7-12; 10: 141 (abstract no. PB0577).
Newham General Hospital, London, England.
OBJECTIVE: To illustrate with serial photographs the diagnosis, treatment and clinical outcome of bacillary angiomatosis and concomitant peliosis hepatis in a male patient with acquired immunodeficiency syndrome (AIDS) and mycobacterium avium intracellulare infection (MAI). METHODS: The patient developed widespread cutaneous nodules and papules in association with pyrexia, weight loss, severe anaemia and hepatomegaly. Skin biopsy showed histological features of bacillary angiomatosis. Ultrasound scanning revealed an enlarged liver and serial liver enzymes showed raised alkaline phosphatase, aspartate aminotransferase and bilirubin. RESULTS: Treatment with erythromycin in a dose of 500 mg four times daily for four weeks resulted in resolution of skin lesions with a decreased in liver size and an improvement in liver enzymes. DISCUSSION AND CONCLUSION: Bacillary angiomatosis has emerged as a new infection in patients with AIDS. Constitutional symptoms due to disseminated infection are similar to late human immunodeficiency virus (HIV) disease. As bacillary angiomatosis is readily treatable, recognition of this infection hinges on clinical suspicion and histological studies.
Publication Types:
Keywords:
- Acquired Immunodeficiency Syndrome
- Angiomatosis, Bacillary
- Communicable Diseases
- HIV Infections
- HIV Seropositivity
- Humans
- Male
- Mycobacterium avium-intracellulare Infection
- Peliosis Hepatis
- Skin Neoplasms
Other ID:
UI: 102210007
From Meeting Abstracts