Thompson C, Salvato P, Stroud S; International Conference on AIDS.
Int Conf AIDS. 1994 Aug 7-12; 10: 178 (abstract no. PB0727).
Houston Immuno. Institute, TX.
OBJECTIVE: To describe the occurrence of MAIC infection in AIDS-associated acalculous cholecystitis. METHODS: A retrospective study of medical records of 50 HIV-positive gay males with laparoscopic-proven acalculous cholecystitis. Ages ranged from 23-48 years with a 3-8 year history of HIV disease. 34 subjects had CD4 counts of < 200. 13 had counts between 200 and 500, and 3 had counts > 500. Subjects were receiving standard antiretroviral therapy and opportunistic infection prophylaxis as indicated. Diagnosis was made on histologic and culture sections of the gallbladder or surrounding lymph nodes and pericholecystic fluid. RESULTS: Twenty pts. (44%) demonstrated MAIC infection, 2 pts. (4%) exhibited another bacterial infection, 4 pts. (8%) manifested a viral pathogen, 3 or 6% showed a protozoal infection and 4 or 8% demonstrated a malignancy. In 15 pts. no associated infective or malignant etiologic agent could be identified. CONCLUSIONS: MAIC was the most prevalent organism identified. Current literature describes only one case of MAIC in association with acalculous cholecystitis and reports cytomegalovirus and cryptosporidium as the most commonly isolated pathogens. MAIC was most prevalent in subjects with CD4 counts < 200, who shared a common background of progressive debilitation, which may have predisposed to gallbladder inflammation and secondary invasion by MAIC.
Publication Types:
Keywords:
- Acalculous Cholecystitis
- Acquired Immunodeficiency Syndrome
- Bacterial Infections
- Cholecystitis
- Communicable Diseases
- Gallbladder
- HIV Infections
- HIV Seropositivity
- Male
- Mycobacterium avium-intracellulare Infection
- Retrospective Studies
Other ID:
UI: 102210172
From Meeting Abstracts