Hasheeve DV, Thompson CE, Salvato PD; International Conference on AIDS.

Int Conf AIDS. 1998; 12: 545 (abstract no. 32127).

Oncol Medica Associates, Houston, TX, USA.

OBJECTIVE: To describe the etiology of acute renal failure (ARF) in a group of hospitalized HIV+ pts. METHOD: A retrospective chart review was conducted on 431 HIV+ pts. hospitalized over a 6-year period. Pts. were defined with acute renal failure if the baseline creatinine increased by at least 2.0 mg%. RESULTS: 129 pts. (30%) met the definition of ARF. Volume depletion from dehydration was the most common etiology occurring in 51 pts.; 2 required dialysis. In 47 pts., nephrotoxic drugs were the responsible agent; 11 required dialysis. Infection was the identified cause in 12 pts.; 2 required dialysis. In 15 pts. renal insufficiency was unexplained and was defined on clinical grounds as AIDS nephropathy, 11 required dialysis. Chronic illness was thought to be the contributing factor in 4 pts.; 2 diabetes, 2 hypertension; all required dialysis. Urinary tract obstruction secondary to tumor was identified in 2 pts., both of which died from their disease within 9 weeks. CONCLUSION: ARF is a common complication in HIV+ pts. ARF is often reversible with proper hydration, aggressive treatment of sepsis, dialysis and careful drug monitoring. Chronic irreversible renal disease was most often due to AIDS nephropathy.

Publication Types:

• Meeting Abstracts

Keywords:

• AIDS-Associated Nephropathy
• Acquired Immunodeficiency Syndrome
• Dialysis
• HIV Infections
• HIV Seropositivity
• Humans
• Kidney Diseases
• Kidney Failure, Acute
• Kidney Failure, Chronic
• Renal Dialysis
• Sepsis
• etiology

Other ID:

• 98396099

UI: 102229642

From Meeting Abstracts