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Community-acquired bacterial and fungal infections in HIV-positive patients hospitalized in AIDS Diagnosis and Therapy Center in Warsaw, Poland.

Stanczak J, Czekalska-Lachowicz E, Skowronska G, Komorowska U, Tobolewska E, Lipniacki A, Horban A; International Conference on AIDS.

Int Conf AIDS. 1998; 12: 776 (abstract no. 41170).

Hospital for Infectious Diseases, Warszawa, Poland.

OBJECTIVE: The aim of presented study was to analyze community-1 acquired infections (recognized in first 48 hours of hospitalization) of HIV-positive patients. MATERIAL AND METHODS: 3146 specimens obtained from 734 HIV-positive patients, hospitalized in AIDS Diagnosis and Therapy Center in Warsaw between January 1996 and December 1997, were tested. Cerebrospinal fluid, blood, urine, sputum, bronchoalveolar lavages and swab samples from rectum, ulcers, abscesses and wounds were analyzed. Microorganisms were identified with culture and biochemical tests, in some cases followed by serological analysis (latex or slide agglutination). Mycobacterium sp. and Cl. difficile detection was supported and verified with Polymerase Chain Reaction technique. In this case PCR amplified fragments of DNAs were identified with electrophoretic analysis or hybridization with probes, detected in ELISA test. RESULTS: In 5 cases out of 12 positive cerebrospinal fluid Cryptococcus neoformans was recognized, next was mycobacterial infection-4 cases. Out of 38 positive blood samples 9 were infected with S. aureus. Leading agent of 181 urinary tract infections was E. coli--37 cases and Enterococcus sp.--32 cases. Fungal infections were the most common in bronchopneumonia--in 162 out of 457 cases C. albicans or other Candida were recognized, second agent was S. aureus (49). In 63 cases of ulcer, abscesses or infected wounds dominated S. Aureus--25 isolates. CONCLUSIONS: 1. Infections of respiratory system and urinary tract were the most common in analyzed group of HIV-infected patients. 2. In our study Candida albicans, S. aureus and E. coli were recognized as leading agents of community-acquired infections of HIV-positive hospitalized patients.

Publication Types:
  • Meeting Abstracts
Keywords:
  • Abscess
  • Acquired Immunodeficiency Syndrome
  • Candidiasis
  • Community-Acquired Infections
  • Cryptococcosis
  • Cryptococcus neoformans
  • HIV Seropositivity
  • Humans
  • Mycobacterium Infections
  • Mycoses
  • Poland
  • Sjogren's Syndrome
  • Urinary Tract Infections
  • diagnosis
  • microbiology
  • therapy
Other ID:
  • 98402787
UI: 102230819

From Meeting Abstracts




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