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Quality of life before and after lung transplantation: a longitudinal study.

TenVergert EM, Essink-Bot ML, Geertsma A, van der Bij W, de Boer WJ; International Society of Technology Assessment in Health Care. Meeting.

Annu Meet Int Soc Technol Assess Health Care Int Soc Technol Assess Health Care Meet. 1997; 13: 81.

Office for Medical Technology Assessment, University Hospital, Groningen, Netherlands.

OBJECTIVE: To examine the changes in quality of life (QOL) before and after lung transplantation (Lgtx). This study was part of a medical technology assessment of the Dutch Lgtx program. METHODS: Following a longitudinal study design, only patients who were alive and who responded first as transplant candidates, and later as recipients at each point of follow-up were included in the study. Changes in QOL up to 19 months after transplantation will be reported. The results are based on data collected between December 1992 and April 1996. During this period 26 patients completed a standardized self assessment questionnaire before and 1, 4, 7, 13, and 19 months after transplantation. The questionnaire included the Nottingham Health Profile, the State-Trait Anxiety Inventory, the Zung Self-Rating Depression Scale, a self-report Karnofsky Performance Index, and other indicators of QOL. RESULTS: The pre-transplant state can be characterized by psychological distress, a low Karnofsky Index, and physical disturbances. Four months after Lgtx most aspects of psychological functioning improved. The Karnofsky Index and physiological functioning showed an impressive improvement following Lgtx. Dimensions particularly positively affected were mobility, energy, and sleep. These improvements were maintained in the following 1.5 year. CONCLUSION: Dramatic improvements in QOL occur after Lgtx and remain stable over time.

Publication Types:
  • Meeting Abstracts
Keywords:
  • Heart Transplantation
  • Humans
  • Karnofsky Performance Status
  • Life
  • Longitudinal Studies
  • Lung Transplantation
  • Quality of Life
  • Questionnaires
  • surgery
  • transplantation
  • hsrmtgs
Other ID:
  • HTX/98601547
UI: 102233088

From Meeting Abstracts




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