Badaru SO, Thomas BN, Ariyo FK, Omilabu SA; International Conference on AIDS.
Int Conf AIDS. 2002 Jul 7-12; 14: abstract no. MoPeC3325.
Department of Medical Microbiology and Parasitology, College of Medicine, University of Lagos, Idiaraba,Lagos, Nigeria
BACKGROUND: Since the initial report from the Centres for Disease Control and Prevention (CDC) describing the acquired immunodeficiency syndrome (AIDS) as a an evolving pandemic and disease of enormous significance, Nigeria is yet to have a broad based surveillance report. However, no significant findings were made. Surveillance figures at the national level the WHO's estimates for the country. Records of patients referred from primary and secondary health centres and hospital for HIV screening and confirmatory test were undertaken over a 10-year period (1991 and 2000). METHODS: Blood samples were collected by venepuncture, inactivated and then screened with Vironostika HIV Uni-Form II Ag/Ab (Organon Teknika) as ELISA method and Capillus HIV-1/HIV-2 (Trinity Biotech) as latex agglutination. All screened positive samples were subjected to confirmatory test using New Lav Blot 1and 2 (Pasteur Diagnostic Laboratories) as Western Blot method. RESULTS: An average prevalence of 17.79% (n = 12,315) was recorded between 1991 and 2000 with a steady increase from 1.1% in 1991 to 28.56% in 2000. A marginal difference was observed in the sex ratio of infection (female: males-17.85%: 17.74%). Patients aged between ages of 19-45years (96%) constituted the main infected age group against those older than 45 years (3.5%) and 0-18 (0.5%). Eight cases of seroconversion by infants (0-2yrs) were recorded. CONCLUSION: HIV/AIDS prevalence is on increase in Nigeria, most especially in the large capital cities like Lagos. These results affirm the rising trend in infection and implications on the productive age group. The economic and health implications of this finding as well as instructions for the future are discussed. The situation calls for mass campaigns as well as the institution of adequate procedures at the nation's health facilities.
Publication Types:
Keywords:
- Acquired Immunodeficiency Syndrome
- Antibodies
- Blotting, Western
- Enzyme-Linked Immunosorbent Assay
- Female
- HIV
- HIV Antibodies
- HIV Infections
- HIV Seronegativity
- HIV Seropositivity
- HIV-1
- HIV-2
- Humans
- Infant
- Male
- Nigeria
- Prevalence
- Seroepidemiologic Studies
- immunology
Other ID:
UI: 102249973
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