Sanchez-V LO, Franco-M FJ, Perez-R P, Corona-I FP, Romo-G J; International Conference on AIDS.

Int Conf AIDS. 2002 Jul 7-12; 14: abstract no. ThPeB7288.

Microbiology Department, Laboratory of Experimental Pathology of Postrgrade and Research Studies, School of Dentistry UNAM, Distrito Federal, Mexico

BACKGROUND. The aim of the present study was to determine the salivary pH in patients with oral candidosis with and without HIV/AIDS and in a control group, assesing if its variations are related to the disease development, type of candidosis, Candida species, and other present diseases. METHODS. The sample comprised 120 patients from Infectology Unit of General Hospital and from the School of Dentistry: 40 with oral candidiasis with HIV-AIDS, 40 with oral candidiasis without VIH-AIDS, and 40 in control group. A 2ml sample of non estimulated saliva were obtained from each patient. We performed immediate measurement of pH and then inoculated in dextrose Sabouraud agar. Determination of Candida species was performed by API 20 C AUX (BioMeriux France) system. Descriptive statistics and ANOVA were calculated. RESULTS. In the group with HIV-AIDS the mean pH was 6.17, with prevalence of C. albicans type I (87.5%) and pseudomembranous candidosis in 85% primarily affecting the tongue in 75%. In the group without HIV-AIDS the 90% were denture users, the mean pH was 6.29, with prevalence of C. albicans type I (42.5%) and eritematous candidiasis in 75% primarily affecting the palate in 70%. Control group showed a mean pH of 6.78. A statistically significant difference among pH values was found (ANOVA p<0.01). CONCLUSIONS. The present study revealed that Candida developement is favored by acidic pH values, we observed more acidity in saliva of patients with HIV-AIDS, followed by HIV-negative. We conclude that salivary pH with acidic values significantly favors Candida growth, specially C. albicans and C. glabrata species and primarily the pseudomembranous and eritematous clinic types.

Publication Types:

• Meeting Abstracts

Keywords:

• Acquired Immunodeficiency Syndrome
• Candida
• Candidiasis, Oral
• Culture
• France
• HIV Infections
• HIV Seropositivity
• Humans
• Hydrogen-Ion Concentration
• Prevalence
• Saliva
• organization & administration

Other ID:

• GWAIDS0012502

UI: 102250000

From Meeting Abstracts