Vivas-Rosel M, Flores-Abuxapqui J, Puc-Franco M, Heredia-Navarrete R, Castro-Sansores C, Franco-Monsreal J, Rodriguez-Sanchez R; International Conference on AIDS.

Int Conf AIDS. 2002 Jul 7-12; 14: abstract no. C10965.

Centro de Investigaciones Regionales Dr. Hideyo Noguchi Universidad Autonoma de Yucatan, Merida, Yucatan, Mexico

BACKGROUND.- The diarrhoea by Cryptosporidium spp. is a frequently fact associated to HIV infection in developing countries. The aim of this study was to determine the prevalence of Cryptosporidium spp. in patients infected by HIV with diarrhoea and to determine the associated factors to this prevalence. METHODS. Patients infected by HIV, with diarrhoea were included. From each subject were obtained three stool samples. A questionnaire with clinical and epidemiological data was obtained. The prevalence of the Cryptosporidium spp. was determined and the categorical variables were compared through the X2 and / or the Fisher test. RESULTS.- Fifty patients were studied, 48 (96%) men and 2 (4%) women. 38 (76%) subjects were in AIDS stage and 12 (24%) in other stages,. In 25 (50%) patients the diarrhoea was intermittent, in 21 (42%) was chronic and in 4 (8%) was acute; 27 (54%) pacients were having antiretroviral therapy. Cryptosporidium spp. was found in nine patients for a prevalence of 18%. The Cryptosporidium spp. was found frequently in patients with AIDS stage (21% vs. 8%, p=0.4) and less frequently in patients with antiretrovial therapy (15% vs. 22%, p=0.7). The Cryptosporidium spp. was found in patients with chronic and intermittent diarrhoea, but not in those with acute diarrhoea (20% vs. 0%, p=0.4). Statistical difference was not found between others variables and the Cryptosporidium prevalence. CONCLUSIONS.- The Cryptosporidium spp. prevalence was associatted with advanced stage of HIV infection and with antiretrovial therapy absence. This confirm the opportunistic role of the Cryptosporidium spp. and the fact that the antiretroviatl therapy can to improve the diarrhoea and in some cases to disappear Cryptosporidium. The technique used in this study is an appropiate option and is of low cost for Cryptosporidium spp. detection. Others studies has been necessary for to know better the problematic in our patients.

Publication Types:

• Meeting Abstracts

Keywords:

• Acquired Immunodeficiency Syndrome
• Animals
• Cryptosporidium
• Developing Countries
• Diarrhea
• Female
• HIV Infections
• HIV Seropositivity
• Humans
• Male
• Mexico
• Prevalence

Other ID:

• GWAIDS0020737

UI: 102259806

From Meeting Abstracts