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Sex differences in adjusted hospital mortality associated with coronary artery bypass surgery in Spain.

Sarria-Santamera A, Palma-Ruiz M; International Society of Technology Assessment in Health Care. Meeting (19th : 2003 : Canmore, Alta.).

Annu Meet Int Soc Technol Assess Health Care Int Soc Technol Assess Health Care Meet. 2003; 19: abstract no. 284.

Spanish Agency for Health Technology Assessment, Sinesio Delgado 6, Madrid, 28029 Spain Tel: +34-91-387-7763, Fax: +34-91-387-7841, E-mail: asarria@isciii.es

OBJECTIVES: Previous international studies have reported an increasing risk of mortality associated with coronary surgery in women. A study of patients undergoing coronary artery bypass graft surgery was conducted in Spain to examine differences in risk adjusted hospital mortality by sex. METHODS: Using an administrative data base, outcome data on the 1783 patients (21.3% women) undergoing this operation in the hospitals located in the region of Madrid in 2001 were examined for differences in patient, disease, and treatment factors. Using multiple logistic regression analysis adjusted mortality odds ratios and 95% confidence intervals were calculated. RESULTS: Compared to men, women were older (mean age 70.5 (69.6-71.3)) than men (mean age 65.6 (65.1-66.1)) and showed a higher prevalence of risk factors. The overall mortality rate during hospitalization was 12.4% among the women and 6.5% among the men. After adjusting for age and risk factors (peripheral vascular disease, congestive heart failure, chronic lung disease, cerebrovascular disease, myocardial infarction, kidney disease) the odds of death were 1.99 (1.33-2.99) greater for women than for men. DISCUSSION: After controlling for relevant risk factors, women undergoing coronary artery bypass surgery in Spain are at a higher risk of in-hospital death than men. Additional investigation is needed to determine the reasons associated with the excess risk of hospital mortality among women.

Publication Types:
  • Meeting Abstracts
Keywords:
  • Coronary Artery Bypass
  • Female
  • Hospital Mortality
  • Hospitalization
  • Humans
  • Male
  • Myocardial Infarction
  • Odds Ratio
  • Regression Analysis
  • Risk Factors
  • Sex Characteristics
  • Spain
  • mortality
  • surgery
  • hsrmtgs
Other ID:
  • GWHSR0004517
UI: 102276202

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