Arvanitis M, Nikolopoulos G, Masgala A, Paraskeva D, Eleni E; International Conference on AIDS (15th : 2004 : Bangkok, Thailand).

Int Conf AIDS. 2004 Jul 11-16; 15: abstract no. C10157.

Hellenic Centre for Infectious Diseases Control, Athens, Greece

Background: To estimate trends in the incidence of parasitic infections as AIDS defining conditions in AIDS patients in Greece. Among 2394 reported AIDS cases, 124 developed one of the parasitic infections related to AIDS at the time of diagnosis. Toxoplasmosis of brain, cryptosporidiosis and isosporiasis were presented at 92, 30 and 2 cases respectively. Methods: Retrospective study. Data originate from the national HIV/AIDS surveillance system. Statistical analysis: logistic regression. Gender, age, and year of diagnosis were included in the analysis. Cases were assigned to two groups according to the time of diagnosis (until or after 1996 when HAART was initiated in Greece). Results: Declining trend of the number of parasitic infections was observed after 1996 due to decline of the total number of AIDS cases. Nevertheless, presence of parasitic infection at time of diagnosis was significantly associated with the year of diagnosis. Patients presenting AIDS were 15.9% more likely to present a parasitic infection at each consecutive year (p value:<0.001). Cases diagnosed during meta-HAART era had almost two times the odds of presenting a parasitic infection comparing to cases diagnosed during pre-HAART era (p value:<0.001). Results did not differentiate for each one of parasitic infections. Cases diagnosed as AIDS in the meta-HAART era were 91% (p value: 0.002) and 157% (p value: 0.011) more likely to present toxoplasmosis of brain and cryptosporidiosis respectively. Only two cases presented isosporiasis at the time of diagnosis. Conclusions: Decline of the number of cases presenting a parasitic infection at the time of diagnosis after 1996 is attributed to the reduction of the total number of AIDS cases. The incidence of such infections among AIDS cases is significantly increasing year by year. AIDS cases diagnosed in the meta-HAART era have higher odds of presenting toxoplasmosis of brain or cryptosporidiosis.

Publication Types:

• Meeting Abstracts

Keywords:

• Acquired Immunodeficiency Syndrome
• Animals
• Antiretroviral Therapy, Highly Active
• Cryptosporidiosis
• Greece
• HIV Infections
• HIV Seropositivity
• Humans
• Incidence
• Isosporiasis
• Retrospective Studies
• Toxoplasmosis
• epidemiology
• trends

Other ID:

• GWAIDS0032828

UI: 102277042

From Meeting Abstracts